MOLECULAR BIOLOGY
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Steve0000
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BIOLOGY
Molecular Biology
Phosducin-Transducin Complex
A molecular duel in the eye controls how we see light and darkness
6 hours ago
0
How does phosphorylation of phosducin affect its interaction with transducin and visual signal transduction?
Phosphorylation increases phosducin's binding to transducin, permanently inhibiting visual signal transduction.
Phosphorylation causes phosducin to degrade, which stops all interaction with transducin.
Phosphorylation reduces phosducin's affinity for transducin's beta-gamma subunits, freeing them to propagate the visual signal.
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Underground
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BIOLOGY
Molecular Biology
Post-translational Modification
Molecular edits after protein synthesis unlock hidden layers of cellular control
12 hours ago
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Why are post-translational modifications essential for protein function beyond genetic coding?
Because they change the DNA sequence to produce different proteins.
Because proteins are fully functional immediately after synthesis without any modifications.
Because they chemically alter proteins to diversify and regulate their activity after synthesis.
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Brewster
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BIOLOGY
Molecular Biology
Alpha Helix
The alpha helix’s elegant coil is a hidden architect of protein function and stability
13 hours ago
0
What is the primary force stabilizing the alpha helix structure in proteins?
Hydrogen bonds between backbone atoms every four amino acids
Ionic bonds between side chains
Random interactions between amino acid side chains
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Perfect_Peter_John_
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BIOLOGY
Molecular Biology
Troponin C
Calcium’s binding to Troponin C flips the switch that powers every heartbeat and muscle move
24 hours ago
0
What critical role does the N lobe of Troponin C play in muscle contraction?
It binds calcium ions and triggers conformational changes that enable muscle contraction.
It binds magnesium ions to initiate muscle contraction.
It acts as a structural anchor without interacting with calcium.
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BIOLOGY
Molecular Biology
Basic Helix-Loop-Helix Motif
A tiny protein twist controls vast genetic programs shaping life’s diversity
24 hours ago
0
How does the dimerization of basic helix-loop-helix proteins influence gene regulation?
It causes the proteins to degrade, preventing gene regulation.
It enables the proteins to bind specific DNA sequences and regulate gene expression.
It changes the proteins into enzymes that modify DNA chemically.
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Bonbo
Me as you
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Molecular Biology
DNA
DNA’s double helix embodies the tension between life’s stability and change
29 hours ago
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What structural feature of DNA allows it to both preserve genetic information and enable evolutionary change?
Its double helix structure that enables replication and mutation
Its single-stranded structure that allows for rapid copying
Its protein composition that controls genetic stability
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BIOLOGY
Molecular Biology
Spliceosome Assembly
Molecular editors splice RNA with precision that shapes life's diversity
40 hours ago
0
What is the primary consequence of the stepwise assembly of the spliceosome on pre-mRNA processing?
It enables precise removal of introns and joining of exons to produce mature mRNA.
It causes the degradation of the entire pre-mRNA transcript.
It randomly cuts RNA sequences without regard to gene expression.
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Molecular Biology
Gene Regulatory Networks
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Molecular networks sculpting life’s diversity through gene expression control
41 hours ago
Gene regulatory networks (GRNs) are the unseen masterminds behind the intricate choreography of life, dictating which genes switch on or off to sculpt the identity and function of every cell. These networks are not just...
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BIOLOGY
Molecular Biology
DNA
The twisted ladder of DNA holds the secrets to life's blueprint and inheritance
2 days ago
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How does the specific base pairing in DNA contribute to genetic fidelity during cell division?
It ensures accurate copying of genetic information by pairing adenine with thymine and cytosine with guanine.
It allows random pairing of bases to increase genetic diversity during cell division.
Base pairing is irrelevant because DNA replication does not depend on nucleotide matching.
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BIOLOGY
Molecular Biology
RNA Interference
A natural cellular defense mechanism became a powerful tool for gene therapy innovation
3 days ago
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What makes RNA interference a more precise method for gene suppression compared to earlier techniques?
It uses double-stranded RNA molecules that specifically target complementary mRNA sequences, minimizing off-target effects.
It randomly degrades all RNA molecules in the cell, ensuring complete gene silencing.
It enhances gene expression by increasing mRNA stability rather than suppressing it.
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MOLECULAR BIOLOGY
Chromatin Structure
Histone Octamer
Histone octamers balance DNA compaction with gene accessibility in a molecular tug-of-war
3 days ago
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What is the primary reason the histone octamer-DNA interaction relies on weak bonds like hydrogen bonds and salt bridges?
To permanently lock DNA in place for maximum stability
To allow DNA to reposition or temporarily detach for gene regulation
To prevent any interaction between DNA and histones
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MOLECULAR BIOLOGY
Genetics and Genomics
ORF1 Protein of LINE1 Elements
A single protein drives a genomic element that shapes 17% of human DNA
4 days ago
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What is the primary role of the ORF1 protein in LINE1 elements and how does it affect the genome?
ORF1 repairs DNA damage caused by LINE1 insertions to maintain genome stability.
ORF1 binds LINE1 RNA to enable retrotransposition, which increases genome variability but can cause instability.
ORF1 prevents LINE1 elements from moving, thereby protecting the genome from mutations.
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Johnbarrow
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BIOLOGY
Molecular Biology
Transfer RNA
Tiny RNA molecules orchestrate the precise assembly of life's building blocks
4 days ago
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What is the primary role of transfer RNA (tRNA) in protein synthesis?
To replicate DNA strands before cell division
To carry specific amino acids and match their anticodons to mRNA codons during translation
To transcribe DNA into messenger RNA
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PistonHeads
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BIOLOGY
Molecular Biology
Nitrogenous Base
Tiny chemical tweaks in nitrogenous bases shape the stability and evolution of genetic codes
4 days ago
0
How does the chemical difference between thymine and uracil influence their role in nucleic acids?
Thymine and uracil are identical and interchangeable in both DNA and RNA.
Uracil contains a methyl group that makes RNA more stable than DNA.
The presence of a methyl group in thymine makes DNA more stable, while uracil without it is used in RNA.
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Brewster
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BIOLOGY
Molecular Biology
Proteins
Proteins wage a molecular war between shape and function that defines life itself
4 days ago
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How does the amino acid sequence of a protein influence its function?
It determines the protein's 3D structure, which dictates its activity.
It only affects the protein's size, not its function.
Proteins function independently of their amino acid sequence.
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BIOLOGY
Molecular Biology
Troponin I
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A muscle protein that doubles as a lifesaving heart attack signal
5 days ago
Contrary to popular belief, Troponin I is not just a passive marker for heart attacks but a dynamic regulator of muscle contraction. This protein plays a crucial role in controlling the interaction between actin and...
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BIOLOGY
Molecular Biology
Prokaryotic Translation
Bacterial ribosomes reveal vulnerabilities exploited by life-saving antibiotics
5 days ago
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What unique feature of prokaryotic translation allows it to be coupled with transcription?
The presence of the 80S ribosome enables coupling of transcription and translation.
The Shine-Dalgarno sequence prevents simultaneous transcription and translation.
The absence of a nuclear membrane allows simultaneous transcription and translation.
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Steeeve
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BIOLOGY
Molecular Biology
Alternative Splicing
A single gene can craft a symphony of proteins through molecular remixing
5 days ago
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How does alternative splicing increase protein diversity from a single gene?
By selectively including or excluding different exons to create multiple RNA variants
By duplicating the gene multiple times to produce different proteins
By mutating the DNA sequence to change the protein produced
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